Molecular Data Guide

The purpose of the Know Your Tumor Molecular Data Guide is to provide SPARK end-users with information and guidance regarding molecular data tables and their descriptions.

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Note:

This data guide assumes a baseline level knowledge of pancreatic cancer, genomic and clinical data and does not cover basic descriptions and explanations.

Data Table NameDescription
G_DNA_CNV_SEGMENTSThis file contains copy number variation (CNV) data derived from an analysis of allele-specific deletions
G_HLAThis file provides human leukocyte antigen (HLA) typing predictions for a given patient
G_INFILTRATIONThis file provides predicted immune infiltration percentages for a tumor sample
G_MOLECULAR_MASTER_FILEThis file provides additional information for the DNA and RNA variants
G_MOLECULAR_MASTER_FILE_FILTEREDThis file provides additional information for the DNA and RNA variants
G_MOLECULAR_METADATAThis file provides metadata pertaining to the samples that have undergone sequencing at Tempus
G_MSIThis file provides microsatellite instability status of a given tumor sample
G_NEOEPITOPE_DNAThis file provides information pertaining to the antigenicity of somatic variants, specific to DNA
G_PIPELINE_VERSIONDetails version of the pipeline
G_RNA_GENE_EXPRESSIONThis file contains raw expression gene counts and normalized transcripts per kilobase million (TPM) that results from the RNA expression pipeline (aligned with Kallisto) at a group level.
G_RNA_TRANSCRIPT_EXPRESSIONThis file contains raw expression transcript counts, transcript length and normalized transcripts per kilobase million (TPM) that result from the RNA expression pipeline (aligned with Kallisto) at a group level.
G_TMBThis file provides tumor mutational burden of a given tumor sample